Thesis

M. M. Silva, "System identification and control for general anesthesia based on parsimonious Wiener models", Licentiate thesis 2012-007, Department of Information Technology, Division of Systems and Control, Uppsala University, Oct. 2012, available at http://www.it.uu.se/research/publications/lic/2012-007/2012-007.pdf.

Journal Papers

[J4] R. Sebastião, M. M. Silva, R. Rabiço, J. Gama, and T. Mendonça, "Real-time algorithm for changes detection in depth of anesthesia signals", Evolving Systems, Springer Berlin / Heidelberg, Volume 4, Issue 1, pp. 3-12, 2013.

[J3] M. M. Silva, J. M. Lemos, A. Coito, B. A. Costa, T. Wigren and T. Mendonca, "Local identifiability and sensitivity analysis of neuromuscular blockade and depth of anesthesia models", submitted to Computer Methods and Programs in Biomedicine, July, 2012.

[J2] M. M. Silva, T. Wigren, and T. Mendonça, "Nonlinear identification of a minimal Neuromuscular Blockade model in anesthesia", IEEE Trans. Contr. Sys. Tech., vol. 20, no. 1, pp. 181-188, Jan. 2012.

[J1] M. M. Silva, T. Wigren, and T. Mendonça, "Identification of the BIS and SE in anaesthesia using a new minimally parameterized nonlinear MIMO model", submitted to Int. J. Adaptive, Control, Signal Processing, Jun. 2010.

Conference Proceedings

[C20] D. V. Caiado, J. M. Lemos, B. A. Costa, M. M. Silva and T. F. Mendonça, "Design of depth of anesthesia controllers in the presence of model uncertainty", submitted to 21th Mediterranean Conference on Control and Automation (MED'13), Crete, Greece, June 25-28, 2013.

[C19] L. A. Paz, M. M. Silva, S.Esteves and T. Mendonça, "Self-calibrating total-mass controller for the neuromuscular blockade
matching the anesthesiologists´ mindset", submitted to 21th Mediterranean Conference on Control and Automation (MED'13), Crete, Greece, June 25-28, 2013.

[C18] M. M. Silva, T. Wigren, A. M. Medvedev and T. Mendonça, "Quantification of the multiplicative uncertainty in the linearized minimally parameterized parsimonious Wiener model for the neuromuscular blockade in closed-loop anesthesia", submitted to 21th Mediterranean Conference on Control and Automation (MED'13), Crete, Greece, June 25-28, 2013.

[C17] M. M. Silva, T. Wigren and T. Mendonça, "Exactly linearizing adaptive control of propofol and remifentanil using a reduced Wiener model for the depth of anesthesia", Proc. 51st IEEE Conference on Decision and Control (CDC'12), Maui, HI, USA, pp. 368-373, 10-13 Dec., 2012.

[C16] R. Sebastião, M. M. Silva, R. Rabiço, J. Gama, and T. Mendonça, "Online evaluation of a changes detection algorithm for depth of anesthesia signals", Proc. 8th IFAC Symposium on Biological and Medical Systems (IFAC BMS'12), Budapest, Hungary, A-0076, 29-31 Aug., 2012 (invited session paper).

[C15] M. M. Silva, R. Rabiço, T. Mendonça and T. Wigren, "Control of rocuronium-induced neuromuscular blockade via online identification of a two-parameters Wiener model", Proc. 16th IFAC Symposium on System Identification (SYSID'12), Brussels, Belgium, pp. 571-576, 11-13 Jul., 2012 (invited session paper).

[C14] T. Mendonça, H. Alonso, M. M. Silva, S. Esteves, and M. Seabra, "Comparing different identification approaches for the depth of anesthesia using BIS measurements", Proc. 16th IFAC Symposium on System Identification (SYSID'12), Brussels, Belgium, pp. 781-785, 11-13 Jul., 2012 (invited session paper).

[C13] R. Sebastião, M. M. Silva, J. Gama, and T. Mendonça, "Contributions to a Decision Support System Based on Depth of Anesthesia Signals", Proc. 25th IEEE International Symposium on Computer-Based Medical Systems (CBMS'12), June 20-22, Rome, Italy, 2012.

[C12] M. M. Silva, and T. Wigren, "Adaptive control of propofol-induced hypnosis in anesthesia using a minimally parameterized Wiener model", Proc. Reglermöte, Uppsala, Sweden, 13-14 Jun., 2012.

[C11] M. M. Silva, T. Mendonça, and T. Wigren, "Nonlinear adaptive control of the neuromuscular blockade level in anesthesia", Proc. 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC'11), Orlando, USA, pp. 41-46, 12-15 Dec., 2011.

[C10] M. M. Silva, "Prediction error identification of minimally parameterized Wiener models in anesthesia", Proc. 18th IFAC World Congress, Milan, Italy, pp. 5615-5620, 28 Aug.-2 Sep., 2011.

[C9] J. Almeida, M. M. Silva, T. Mendonça, and P. Rocha, "A compartmental model-based control strategy for NeuroMuscular Blockade level", Proc. 18th IFAC World Congress, Milan, Italy, pp. 599-604, 28 Aug.-2 Sep., 2011.

[C8] R. Sebastião, M. M. Silva, J. Gama, and T. Mendonça, "Contributions to an Advisory System for Changes Detection in Depth of Anesthesia Signals", Learning from Medical Data Streams, 13:th Conference on Artificial Intelligence in Medicine, Bled, Slovenia, 6 Jul., 2011.

[C7] M. M. Silva, J. Almeida, T. Wigren, and T. Mendonça, "Merging PK/PD information in a minimally parameterized model of the NeuroMuscular Blockade", Proc. 32nd Int. Conference of the IEEE EMBS (EMBC'10), Buenos Aires, Argentine, pp. 4602-4605, 31 Aug.-4 Sep., 2010.

[C6] M. M. Silva, T. Mendonça, and T. Wigren, "Online Nonlinear Identification of the Effect of Drugs in Anaesthesia Using a Minimal Parameterization and BIS Measurements", Proc. American Control Conference (ACC'10), Baltimore, MD, USA, pp. 4379 - 4384, 30 Jun.-2 Jul., 2010. [Best Presentation in Session]

[C5] J. Almeida, M. M. Silva, T. Wigren, and T. Mendonça, "Contributions to the initialization of online identification algorithms for anaesthesia: the NeuroMuscular Blockade case study", Proc. 18th Mediterranean Conference on Automation and Control (MED'10), Marrakech, Morocco, pp. 1341 - 1346, 23-25 Jun., 2010.

[C4] B. A. Costa, M. M. Silva, T. Mendonça, and J. M. Lemos, "Neuromuscular blockade nonlinear model identification", Proc. 17th Mediterranean Conference on Automation and Control (MED'09), Thessaloniki, Greece, pp.1137-1142, 24-26 Jun., 2009.

[C3] M. M. Silva, C. Sousa, R. Sebastião, J. Gama, T. Mendonça, P. Rocha, and S. Esteves, "Total Mass TCI driven by parametric estimation," Proc. 17th Mediterranean Conference on Automation and Control (MED'09), Thessaloniki, Greece, pp. 1149-1154, 24-26 Jun., 2009.

[C2] M. M. Silva, H. Alonso, J. M. Lemos, and T. Mendonça, "An Adaptive Approach to Target Controlled Infusion", Proc. 10th European Control Conference (ECC'09), Budapest, Hungary, 23-26 Aug., pp. 418-423, 2009.

[C1] M. M. Silva, T. Mendonça, and S. Esteves, "Personalized neuromuscular blockade through control: Clinical and technical evaluation," Proc. 30th Int. Conference of the IEEE EMBS (EMBC'08), Vancouver, Canada, pp.5826-5829, 20-25 Aug., 2008 (invited session paper).

Technical Reports

[TR3] M. M. Silva, T. Wigren, and T. Mendonça. "An Adaptive Controller for Propofol in Anesthesia under Synergistic Remifentanil Disturbances", Technical Report 2012-011, May 2012, available at http://www.it.uu.se/research/publications/reports/2012-011/.

[TR2] M. M. Silva, T. Mendonça, and T. Wigren. "Online Nonlinear Identification of the Effect of Drugs in Anaesthesia Using a Minimal Parameterization and BIS Measurements", Technical Report 2010-008, Mar. 2010, available at http://www.it.uu.se/research/publications/reports/2010-008/.

[TR1] M. M. Silva, T. Wigren, and T. Mendonça. "Nonlinear Identification of a Minimal NeuroMuscular Blockade Model in Anaesthesia", Technical Report 2009-023, Sep. 2009, available at http://www.it.uu.se/research/publications/reports/2009-023/.

Other

[A8] M. M. Silva, T. Wigren, T. Mendonça, E. W. Jensen, and P. Gambús, "Sedation-analgesia with Propofol and Remifentanil: new model for individualized BIS prediction", Proc. American Society of Anesthesiology Annual Meeting, Chicago, Il, USA, Oct. 2011 (abstract A511 - poster presentation).

[A7] R. Sebastião, M. M. Silva, S. Esteves, T. Fernandes, M. Seabra, J. Gama, and T. Mendonça, "Contributions to a Decision Support System Based on Depth of Anesthesia Signals", Proc. American Society of Anesthesiology Annual Meeting, Chicago, Il, USA, Oct. 2011 (abstract A1285 - poster presentation).

[A6] J. Almeida, M. M. Silva, T. Mendonça, P. Rocha, and S. Esteves, "A control strategy for a new minimal parameterized compartmental model for NMB level", Proc. American Society of Anesthesiology Annual Meeting, Chicago, Il, USA, Oct. 2011 (abstract A1659 - poster presentation).

[A5] L. A. Paz, J. Almeida, M. M. Silva, T. Mendonça, S. Esteves, and B. A. Costa, "Integrated design system for monitoring, digital processing and control in anesthesia", Proc. American Society of Anesthesiology Annual Meeting, Chicago, Il, USA, Oct. 2011 (abstract A1169 - oral presentation).

[A4] M. M. Silva, "Prediction error identification algorithms for anesthesia-related Wiener models", 6th Swedish-Russian Control Conference, St. Petersburg, Russia, 19-20 Sep., 2011 (oral presentation).

[A3] C. Sousa, S. Esteves, M. M. Silva, T. Mendonça, and P. Rocha, "Total Mass Target Controlled Infusion (TM-TCI)", 2nd World Congress of Total Intravenous Anaesthesia and Target Controlled Infusion (TIVA-TCI'09), Berlin, Germany, 23-25 Apr., 2009 (oral presentation).

[A2] R. Sebastião, M. M. Silva, S. Esteves, J. Gama, and T. Mendonça, "Online Tuned Algorithm for Recovery Detection (OLARD)", 2nd World Congress of Total Intravenous Anaesthesia and Target Controlled Infusion (TIVA-TCI'09), Berlin, Germany, 23-25 Apr., 2009 (poster presentation).

[A1] M. M. Silva, S. Esteves, F. N. Nogueira, J. M. Lemos, and T. Mendonça, "E-TCI (Enhanced- Target Controlled Infusion) driven by online parametric estimation", 2nd World Congress of Total Intravenous Anaesthesia and Target Controlled Infusion (TIVA-TCI'09), Berlin, Germany, 23-25 Apr., 2009 (poster presentation).