Uppsala University Department of Information Technology

Technical Report 2010-001

Computational and Visualization tools for Genetic Analysis of Complex Traits

Mahen Jayawardena, Salman Toor, and Sverker Holmgren

January 2010


We present grid based tools for simultaneous mapping of multiple locations (QTL) in the genome that affect quantitative traits (e.g. body weight, blood pressure) in experimental populations. The corresponding computational problem is very computationally intensive. We have earlier shown that, using appropriate parallelization schemes, this type of application is suitable for deployment on grid systems.

A grid portal interface is often an ideal tool for biologists performing advanced genetic analysis. We describe an implementation of such a portal system and how it is used for performing multidimensional QTL searches efficiently.

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